Author

M. Brueggemann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. D. Baldus· 2 shared G. Cario· 2 shared T. Beder· 2 shared A. Attarbaschi· 1 shared A. Beishuizen· 1 shared A. K. Bergmann· 1 shared A. Koenigs· 1 shared A. M. Hartmann· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

C. D. Baldus

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3 papers

Recent·Most cited

Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations

A. Pacholewska, M. Lienhard, M. Brueggemann, H. Haenel, L. Bilalli, A. Koenigs, K. Becker, K. Koehrer, J. Kaiser, H. Gohlke, N. Gattermann, M. Hallek, C. D. Herling, J. Koenig, C. Grimm, , M. R. Schweiger

This study uses long-read transcriptome sequencing to analyze SF3B1 mutations in CLL and MDS patients, revealing common splicing alterations and their impact on disease prognosis.

bioRxiv · Jan 26, 2024Cancer Biology

Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma

E. Kroeze, I. Iaccarino, M. M. Kleisman, M. Mondal, T. Beder, M. Khouja, M. P. Hoeppner, M. Scheijde-Vermeulen, L. A. Kester, M. Brueggemann, C. D. Baldus, G. Cario, R. S. Bladergroen, N. Garnier, A. Attarbaschi, , W. Klapper

This study presents the first comprehensive mutational and transcriptional analysis of B-cell precursor lymphoblastic lymphoma (BCP-LBL), revealing molecular similarities to BCP-ALL but with distinct mutation patterns in epigenetic modifiers.

bioRxiv · Dec 27, 2023Cancer Biology

The gene expression classifier ALLCatchR identifies B-precursor ALL subtypes and underlying developmental trajectories across age

T. Beder, B.-T. Hansen, A. M. Hartmann, J. Zimmermann, E. Amelunxen, N. Wolgast, W. Walter, M. Zaliova, Z. Antic, P. Chouvarine, L. Bartsch, M. Barz, M. Bultmann, J. Horns, S. Bendig, , L. Bastian

ALLCatchR, a machine learning classifier, accurately assigns B-precursor ALL samples to molecular subtypes and identifies developmental trajectories using RNA-Seq data.

bioRxiv · Feb 1, 2023 · PreprintCancer Biology