The RAF oncogenes of vertebrates are ohnologs that derive from the two rounds of whole-genome duplications early in vertebrate evolution
A. Coward Black, M. C. Bailey, M. J. Ruane-Foster, J. C. Opazo, F. Hoffmann
This study investigates the evolutionary origin of vertebrate RAF genes, finding they arose from two rounds of whole-genome duplications, with B-RAF showing stronger cancer associations.
bioRxiv · Sep 12, 2019 · PreprintEvolutionary Biology