Cancer BiologybioRxiv
Integrating genetic dependencies and genomic alterations across pathways and cancer types
T. Y. Park, M. D. M. Leiserson, G. W. Klau, B. J. Raphael
The paper introduces SuperDendrix to analyze genetic dependencies and genomic alterations across cancer cell lines, revealing pathway-specific associations and lineage-specific transcription factor dependencies.
DOI 10.1016/j.xgen.2022.100099