An inimitable proprotein convertase subtilisin kexin-9 (PCSK9) cleavage site VFAQ on Spike protein along with furin cleavage site makes SARS-CoV-2 unique
M. D. Pandya, D. Shukla, S. Shah, K. Das, S. Dave, J. Das
The paper identifies a novel PCSK9 cleavage site in SARS-CoV-2 Spike protein and suggests its combination with the furin site contributes to the virus's uniqueness in pathogenicity and drug development.
bioRxiv · May 4, 2023 · PreprintEvolutionary Biology