Comparative analysis defines a broader FMRFamide-gated sodium channel family and determinants of neuropeptide sensitivity
M. Dandamudi, H. Hausen, T. Lynagh
The paper identifies amino acid residues determining FMRFamide activity at FaNaC channels and shows evolutionary conservation of ligand recognition determinants across DEG/ENaC channels.
bioRxiv · Mar 23, 2022Biochemistry