Nijmegen Breakage Syndrome (NBS) is a telomeropathy: analysis of telomere length in NBS homo- and heterozygotes and humanized Nbs ice
R. Habib, R. Kim, H. Neitzel, I. Demuth, K. Chrzanowska, E. Seemanova, R. Faber, M. Digweed, K. Jäger, K. Sperling, M. Walter
This study shows that Nijmegen Breakage Syndrome (NBS) is a telomeropathy, with reduced telomere length in patients, and explores its dual role in cancer susceptibility and survival.
bioRxiv · Mar 7, 2019 · PreprintCancer Biology