The mechanism of Hsp90-induced oligomerization of Tau
S. Weickert, M. Wawrzyniuk, L. John, S. G. D. Rüdiger, M. Drescher
This study investigates how Hsp90 induces Tau oligomerization by promoting an open conformation that exposes aggregation-prone regions, while inhibiting fibril formation.
bioRxiv · Nov 27, 2019 · PreprintBiophysics