Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma
M. M. Peshoff, P. Gupta, R. Trivedi, S. Oberai, P. Chakrapani, M. Dang, N. K. Milam, M. E. Maynard, B. D. Vaillant, J. T. Huse, L. Wang, K. Clise-Dwyer, K. P. Bhat
This study shows TREM2 promotes phagocytosis in gliomas and is not linked to immunosuppression, suggesting TREM2 activation could enhance immunotherapy for brain tumors.
bioRxiv · Apr 5, 2023Cancer Biology