Author

M. E. Rognes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biophysics· 1 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 1 Assay:clinical cohort / trial· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

V. Vinje· 5 shared K.-A. Mardal· 2 shared A. Eklund· 1 shared A. Frigessi· 1 shared A. Kohn-Luque· 1 shared A.-L. Boerresen-Dale· 1 shared C. Daversin-Catty· 1 shared E. F. Borgen· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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5 shared papersBioengineering

V. Vinje

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Are brain displacements and pressures within the parenchyma induced by surface pressure differences? A computational modelling study

E. Piersanti, M. E. Rognes, V. Vinje

This study models brain parenchyma as elastic or poroelastic to assess if surface pressure differences drive intracranial fluid flow, finding they do not propagate through the parenchyma.

bioRxiv · Sep 7, 2022 · PreprintBioengineering

Human intracranial pulsatility during the cardiac cycle: a computational modelling framework

M. Causemann, V. Vinje, M. E. Rognes

This paper develops a computational model of intracranial dynamics to simulate brain pulsatility during the cardiac cycle and validates it against clinical indicators.

bioRxiv · May 19, 2022Biophysics

Brain solute transport is more rapid in periarterial than perivenous spaces

V. Vinje, E. N. T. P. Bakker, M. E. Rognes

The paper compares fluid flow and solute transport in periarterial and perivenous brain spaces using computational modeling, finding faster transport in periarterial spaces due to geometric differences.

bioRxiv · Mar 23, 2021Bioengineering

The mechanisms behind perivascular fluid flow

C. Daversin-Catty, V. Vinje, K.-A. Mardal, M. E. Rognes

This study uses computational fluid dynamics to show that arterial wall expansion, rigid motions, and a small static CSF pressure gradient generate net and oscillatory perivascular fluid flow, matching experimental observations.

bioRxiv · Jun 17, 2020Physiology

Intracranial pressure elevation alters CSF clearance pathways

V. Vinje, A. Eklund, K.-A. Mardal, M. E. Rognes, K.-H. Stoverud

This study examines how intracranial pressure affects CSF clearance pathways using a mathematical model, finding that arachnoid granulations dominate outflow under elevated pressure.

bioRxiv · Sep 8, 2019Bioengineering

Towards personalized computer simulation of breast cancer treatment: a multi-scale pharmacokinetic and pharmacodynamic model informed by multi-type patient data

X. Lai, O. Geier, T. Fleischer, O. Garred, E. F. Borgen, S. Funke, S. Kumar, M. E. Rognes, T. Seierstad, A.-L. Boerresen-Dale, V. N. Kristensen, O. Engebraaten, A. Kohn-Luque, A. Frigessi

This study develops a multi-scale pharmacokinetic and pharmacodynamic model of breast cancer treatment, personalized with patient data to simulate and improve treatment outcomes.

bioRxiv · Jul 19, 2018Cancer Biology