Pinpointing the tumor-specific T-cells via TCR clusters
M. Goncharov, E. A. Bryushkova, N. I. Sharayev, V. D. Skatova, A. M. Baryshnikova, G. V. Sharonov, I. V. Samoylenko, L. V. Demidov, D. M. Chudakov, E. O. Serebrovskaya
This paper demonstrates using TCR repertoires homology cluster analysis to identify tumor-reactive T cells and improve TIL culturing and enrichment.
bioRxiv · Jan 30, 2022Immunology