Author

M. I. Katsnelson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 5

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:chromatin & epigenetic regulation· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:mechanistic / dynamical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

E. V. Koonin· 5 shared Y. I. Wolf· 4 shared J. A. Cuesta· 1 shared J. Iranzo· 1 shared S. Manrubia· 1 shared Y. Bakhtin· 1 shared

Activity by Year

2017-2020 · peak 3/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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5 shared papersEvolutionary Biology

E. V. Koonin

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5 papers

Recent·Most cited

Punctuated equilibrium as the default mode of evolution of large populations on fitness landscapes dominated by saddle points in the weak-mutation limit

Y. Bakhtin, M. I. Katsnelson, Y. I. Wolf, E. V. Koonin

The paper shows that in large populations with weak mutation rates, evolution primarily occurs in stasis near saddle points on fitness landscapes, with rapid transitions between these points when beneficial mutations are fixed.

bioRxiv · Jul 20, 2020 · PreprintEvolutionary Biology

On the feasibility of saltational evolution

M. I. Katsnelson, Y. I. Wolf, E. V. Koonin

The paper examines the probability of multi-mutational leaps in evolution and finds they are rare under typical conditions but could be significant in specific scenarios like population bottlenecks.

bioRxiv · Aug 23, 2018Evolutionary Biology

Towards physical principles of biological evolution

M. I. Katsnelson, Y. I. Wolf, E. V. Koonin

This paper explores analogies between physical principles and biological evolution, suggesting that concepts like frustration and percolation may explain the emergence of biological complexity.

bioRxiv · Aug 30, 2017Evolutionary Biology

Inevitability of the emergence and persistence of genetic parasites caused by thermodynamic instability of parasite-free states

E. V. Koonin, Y. I. Wolf, M. I. Katsnelson

The paper demonstrates that genetic parasites are inevitable due to thermodynamic instability of parasite-free states in replicator systems.

bioRxiv · Aug 30, 2017Evolutionary Biology

Disentangling The Effects Of Selection And Loss Bias On Gene Dynamics

J. Iranzo, J. A. Cuesta, S. Manrubia, M. I. Katsnelson, E. V. Koonin

The paper estimates the relative contributions of selection and loss bias to gene dynamics in prokaryotes using mathematical modeling and comparative genomics.

Proceedings of the National Academy of Sciences · Jun 26, 2017Peer-reviewedEvolutionary Biology