Incomplete transcriptional dosage compensation of vertebrate sex chromosomes is balanced by post-transcriptional compensation.
N. C. Lister, A. M. Milton, H. R. Patel, S. Waters, B. J. Hanrahan, K. L. McIntyre, A. M. Livernois, L. K. Wee, A. R. Ringel, S. Mundlos, M. I. Robson, L. Shearwin-Whyatt, F. Grutzner, J. A. Marshall Graves, A. Ruiz-Herrera, P. D. Waters
The paper shows that sex chromosome gene dosage imbalance is compensated by post-transcriptional mechanisms in platypus and chicken, achieving equal protein levels between sexes.
bioRxiv · Feb 23, 2023Evolutionary Biology