M. J. Guberman-Pfeffer

Redox Conduction Through Cytochrome 'Nanowires' Can Sustain Cellular Respiration

The paper investigates redox conduction through cytochrome nanowires in Geobacter sulfurreducens using computational methods to model electron transfer mechanisms and their physiological relevance.

Delineating redox cooperativity in water-soluble and membrane multiheme cytochromes through protein design

This study uses de novo protein design to investigate redox cooperativity in multiheme cytochromes, showing that membrane burial enhances heme-heme electrostatic coupling.

Are Electrical Characterizations Consistent with the Cytochrome Structures of Geobacter 'Nanowires'

The paper re-examines the electrical properties of Geobacter filaments in light of CryoEM structures, finding inconsistencies between functional characterizations and structural data.

From Hot Water to Dry Dirt: Microbes Use Cytochrome 'Nanowires' of Similar Conductivity but Different Structure

The paper computationally assesses redox conductivity in structurally diverse cytochrome nanowires from different organisms, finding similar conductivities despite structural differences.

Structural Determinants of Redox Conduction Favor Robustness over Tunability in Microbial Cytochrome Nanowires

The paper uses molecular dynamics to show that redox conductivity in microbial cytochromes is robust across structural variations, with conductivity sufficient for cellular respiration.

Heme Hopping Falls Short: What Explains Anti-Arrhenius Conductivity in a Multi-heme Cytochrome Nanowire?

The paper investigates the temperature-dependent conductivity of OmcS nanowires, finding that cooling increases conductivity due to changes in hydration shell properties and redox potentials, but solution-phase models fail to replicate experimental results.