Author

B. J. Hardy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

P. Curnow· 2 shared A. Martin Hermosilla· 1 shared A. S. F. Oliveira· 1 shared C. J. Arthur· 1 shared C. V. Robinson· 1 shared C. Williams· 1 shared D. K. Chinthapalli· 1 shared E. L. Bungay· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

P. Curnow

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2 papers

Recent·Most cited

Delineating redox cooperativity in water-soluble and membrane multiheme cytochromes through protein design

B. J. Hardy, P. Dubiel, E. L. Bungay, M. Rudin, C. Williams, C. J. Arthur, M. J. Guberman-Pfeffer, A. S. F. Oliveira, P. Curnow, J. L. R. Anderson

This study uses de novo protein design to investigate redox cooperativity in multiheme cytochromes, showing that membrane burial enhances heme-heme electrostatic coupling.

bioRxiv · Mar 21, 2024Biochemistry

Cellular production of a de novo membrane cytochrome

B. J. Hardy, A. Martin Hermosilla, D. K. Chinthapalli, R. Anderson, C. V. Robinson, P. Curnow

The paper designs and produces a synthetic diheme membrane cytochrome in bacteria that mimics natural electron transport features without natural sequence homology.

bioRxiv · Dec 6, 2022 · PreprintBiochemistry