Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws
M. J. Maristany, A. Aguirre Gonzalez, J. R. Espinosa, J. Huertas, R. Collepardo-Guevara, J. A. Joseph
The paper uses a coarse-grained model to analyze how amino acid mutations affect the stability of prion-like domains across multiple proteins, revealing scaling laws that predict condensate behavior.
bioRxiv · Jun 14, 2023Biophysics