Genomes of the Autonomous Parvovirus Minute Virus of Mice Induce Replication Stress Through RPA Exhaustion
M. K. Haubold, J. N. P. Aquino, S. R. Rubin, I. K. Jones, E. Pham, K. Majumder
This study shows that MVM genomes induce replication stress by sequestering RPA, leading to DNA breaks and host genome vulnerability.
bioRxiv · Feb 13, 2023Microbiology