PhysiologybioRxiv
Molecular mechanisms for intestinal HCO3- secretion and its regulation by guanylin in seawater-acclimated eels
Y. Takei, M. K. S. Wong, M. Ando
This study identifies molecular mechanisms of HCO3- secretion in seawater-acclimated eels, showing guanylin inhibits NKCC2 and activates DRA and NBC transporters to enhance HCO3- flux.
DOI 10.1242/jeb.203539