In vivo suppression of polyglutamine aggregation via co-condensation of the molecular chaperone DNAJB6
E. Preusser de Mattos, M. Kolbe Musskopf, S. Bergink, H. H. Kampinga
This study shows DNAJB6 suppresses polyglutamine aggregation in vivo through co-condensation with mobile polyQ assemblies, preventing their conversion to solid aggregates.
bioRxiv · Aug 23, 2022 · PreprintCell Biology