Translesion Synthesis by MmLV-, AMV-, and HIV-Reverse Transcriptases Using RNA Templates Containing Inosine, Guanosine, and Their 8-oxo-7,8-Dihydropurine Derivatives.
M. J. Resendiz, M. Glennon, A. Skinner, M. Krutsinger
This paper investigates how three reverse transcriptases handle RNA templates with inosine and its oxidized derivatives, finding differences in dNTP incorporation and synthesis efficiency.
bioRxiv · Jun 10, 2020Biochemistry