Redefining CD4 T cell residency: Helper T cells orchestrate protective humoral immunity in the lung
N. Swarnalekha, D. Schreiner, L. C. Litzler, S. Iftikhar, D. Kirchmeier, M. Kuenzli, C. G. King
This study identifies a novel population of long-lived T resident helper (TRH) cells in the lung that require Bcl6 for differentiation and are critical for local antibody production.
bioRxiv · Feb 28, 2020Immunology