A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression
S. Ketharnathan, M. Leask, J. Boocock, A. Phipps-Green, J. Antony, J. O'Sullivan, T. Merriman, J. Horsfield
This study identifies a genetic variant linked to serum urate levels and shows it enhances HNF4A-dependent PDZK1 expression, potentially increasing urate transport.
bioRxiv · Jul 8, 2018Cell Biology