Author

J. Horsfield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Antony· 2 shared A. Phipps-Green· 1 shared G. Gimenez· 1 shared I. M. Morison· 1 shared J. Boocock· 1 shared J. O'Sullivan· 1 shared M. Leask· 1 shared R. C. Day· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

J. Antony

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Author profile →

2 papers

Recent·Most cited

BET inhibition prevents aberrant RUNX1 and ERG transcription in STAG2 mutant leukaemia cells.

J. Antony, G. Gimenez, T. Taylor, U. Khatoon, R. C. Day, I. M. Morison, J. Horsfield

This study shows that BET inhibition reduces aberrant RUNX1 and ERG transcription in STAG2 mutant leukemia cells by blocking enhancer-driven gene expression during differentiation.

bioRxiv · Sep 10, 2019Cancer Biology

A non-coding genetic variant maximally associated with serum urate levels is functionally linked to HNF4A-dependent PDZK1 expression

S. Ketharnathan, M. Leask, J. Boocock, A. Phipps-Green, J. Antony, J. O'Sullivan, T. Merriman, J. Horsfield

This study identifies a genetic variant linked to serum urate levels and shows it enhances HNF4A-dependent PDZK1 expression, potentially increasing urate transport.

bioRxiv · Jul 8, 2018Cell Biology