Graves' disease-associated TSHR gene is demethylated and expressed in human regulatory T cells
A. Salumets, L. Tserel, S. Kasela, M. Limbach, L. Milani, H. Peterson, K. Kisand, P. Peterson
The paper identifies hypomethylation and increased expression of the TSHR gene in regulatory T cells, but finds no methylation changes at the TSHR locus in Graves' disease patients.
bioRxiv · Oct 24, 2022 · PreprintImmunology