Author

K. Kisand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

P. Peterson· 3 shared A. Bhagwat· 1 shared A. Cerutti· 1 shared A. Ranki· 1 shared A. Salumets· 1 shared B. Huang· 1 shared B. Pei· 1 shared B. Q. Vuong· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

P. Peterson

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Author profile →

4 papers

Recent·Most cited

A Germinal Center Checkpoint of AIRE in B Cells Limits Antibody Diversification

J. Z. Zhou, B. Pei, G. Sun, M. Pawlitz, W. Zhang, x. Li, F. Yao, K. C. Hokynar, C.-X. Li, M. L. Perera, S. Wei, S. Zheng, L. A. Polin, J. M. Poulik, A. Ranki, , K. Chen

This study identifies AIRE as a checkpoint in germinal center B cells that limits antibody diversification by inhibiting AID function, leading to autoimmunity and impaired immune responses.

bioRxiv · Jan 10, 2024 · PreprintImmunology

Graves' disease-associated TSHR gene is demethylated and expressed in human regulatory T cells

A. Salumets, L. Tserel, S. Kasela, M. Limbach, L. Milani, H. Peterson, K. Kisand, P. Peterson

The paper identifies hypomethylation and increased expression of the TSHR gene in regulatory T cells, but finds no methylation changes at the TSHR locus in Graves' disease patients.

bioRxiv · Oct 24, 2022 · PreprintImmunology

Aire-dependent transcripts escape H3K36me3 and Raver2 induced alternative splicing to sustain central immune tolerance

F. Padonou, V. Gonzalez, N. Jmari, J. Maslovskaja, K. Kisand, P. Peterson, M. Irla, M. Giraud

The paper identifies that Aire-sensitive genes in mTECs escape Raver2 and H3K36me3 regulation, leading to reduced alternative splicing and impacting central immune tolerance.

bioRxiv · Apr 8, 2021Immunology

Differential levels of IFNα subtypes in autoimmunity and viral infection

V. Bondet, M. P. Rodero, C. Posseme, P. Bost, J. Decalf, L. Haljasmagi, N. Bekaddour, G. Rice, V. Upasani, J.-P. Herbeuval, J. A. Reynolds, T. A. Briggs, I. N. Bruce, C. Mauri, D. Isenberg, , D. Duffy

The paper develops an ultrasensitive ELISA for IFN2 and applies it to study IFN subtype responses in viral infection and autoimmunity, revealing distinct protein ratios and potential auto-antibody effects.

bioRxiv · Mar 4, 2021 · PreprintImmunology