Systematic analysis of key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria
Claire L. Gorrie, Anders Gonçalves da Silva, Danielle J. Ingle, Charlie K. Higgs, Torsten Seemann, Timothy Paul Stinear, Deborah Anne Williamson, Jason C. Kwong, M. Lindsay Grayson, Norelle L. Sherry, Benjamin P. Howden
The paper systematically evaluates key parameters affecting SNP-based transmission inference of MDROs, finding that using a closely-related reference genome and sliding-window analysis improves accuracy.
The Lancet Microbe · Aug 6, 2021Peer-reviewedGenomics