Author

Charlie K. Higgs

The University of MelbourneORCID 0000-0001-7364-7380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

Benjamin P. HowdeniD· 2 shared Claire L. GorrieiD· 2 shared Jason C. KwongiD· 2 shared Norelle L. SherryiD· 2 shared Anders Gonçalves da SilvaiD· 1 shared Caroline L. MarshalliD· 1 shared Caroline Reed· 1 shared Danielle J. IngleiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersGenomics

Benjamin P. HowdenORCID

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2 papers

Recent·Most cited

Systematic analysis of key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria

Claire L. Gorrie, Anders Gonçalves da Silva, Danielle J. Ingle, Charlie K. Higgs, Torsten Seemann, Timothy Paul Stinear, Deborah Anne Williamson, Jason C. Kwong, M. Lindsay Grayson, Norelle L. Sherry, Benjamin P. Howden

The paper systematically evaluates key parameters affecting SNP-based transmission inference of MDROs, finding that using a closely-related reference genome and sliding-window analysis improves accuracy.

The Lancet Microbe · Aug 6, 2021Peer-reviewedGenomics

Genomic interrogation of the burden and transmission of multidrug-resistant pathogens within and across hospital networks

Norelle L. Sherry, Robyn S. Lee, Claire L. Gorrie, Jason C. Kwong, Rhonda L. Stuart, Tony M. Korman, Caroline L. Marshall, Charlie K. Higgs, Hiu Tat Chan, Maryza Graham, Paul D.R. Johnson, Marcel Leroi, Caroline Reed, Michael J. Richards, Monica A. Slavin, , on behalf of the Controlling Superbugs Study Group

The paper uses genomic analysis to assess MDRO transmission within and across hospitals, finding high transmission rates for vanA VRE and linking genomic data with epidemiologic data to evaluate infection control.

bioRxiv · Sep 10, 2019 · PreprintGenomics