Gradual Compaction of the Nascent Peptide During Cotranslational Folding on the Ribosome
M. Liutkute, M. Maiti, E. Samatova, J. Enderlein, M. V. Rodnina
The paper uses FPA and PET-FCS to study cotranslational folding of the HemK N-terminal domain, showing compaction starts early and structural fluctuations decrease as the domain moves away from the ribosome.
eLife · Oct 27, 2020Peer-reviewedBiophysics