M. P. Kirpichnikov

(Re)defining the human chromatome: an integrated meta-analysis of localization, function, abundance, physical properties and domain composition of chromatin proteins

This paper presents a comprehensive meta-analysis of human chromatin proteins, integrating diverse data types to characterize their composition, localization, and functional properties, and introduces a web resource for chromatome research.

Effects of Mutations in the Receptor-Binding Domain of SARS-CoV-2 Spike on its Binding Affinity to ACE2 and Neutralizing Antibodies Revealed by Computational Analysis

This study uses computational analysis to evaluate how mutations in the SARS-CoV-2 Spike protein's RBD affect binding to ACE2 and neutralizing antibodies, identifying high-risk variants with antigenic escape potential.

Histone dynamics mediate DNA unwrapping and sliding in nucleosomes: insights from multi-microsecond molecular dynamics simulations

This study uses molecular dynamics simulations to show how histone dynamics enable DNA unwrapping and sliding in nucleosomes, contributing to chromatin structure and function.