Author

M. R. Domingo-Sananes

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Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

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Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

J. McInerney· 2 shared A. Beavan· 1 shared

Activity by Year

2019-2023 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersEvolutionary Biology

J. McInerney

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2 papers

Recent·Most cited

Evolutionary BiologybioRxivMar 20, 2023

Contingency, Repeatability and Predictability in the Evolution of a Prokaryotic Pangenome.

A. Beavan, M. R. Domingo-Sananes, J. McInerney

This study uses machine learning to predict gene presence/absence in E. coli pangenomes based on accessory genes, showing predictable evolutionary patterns despite genetic diversity.

DOI 10.1073/pnas.2304934120

E. colimachine learning (classical)

𝕏 PostBluesky

MicrobiologybioRxivPreprintOct 21, 2019

Selection-based model of prokaryote pangenomes

M. R. Domingo-Sananes, J. McInerney

This paper develops a mathematical model to explore how gene fitness effects and gain/loss rates influence prokaryote pangenome diversity.

DOI 10.1101/782573

bacteria (other)statistical model

𝕏 PostBluesky