Author

M. R. Vella

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

F. Gould· 2 shared A. B. Shiels· 1 shared A. J. Piaggio· 1 shared A. L. Lloyd· 1 shared A. Lloyd· 1 shared B. Hollingsworth· 1 shared C. E. Gunning· 1 shared D. V. Blondel· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersEvolutionary Biology

F. Gould

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2 papers

Recent·Most cited

Locally Fixed Alleles: A method to localize gene drive to island populations

J. Sudweeks, B. Hollingsworth, D. V. Blondel, K. J. Campbell, S. Dhole, J. D. Eisemann, O. Edwards, J. Godwin, G. R. Howald, K. Oh, A. J. Piaggio, T. A. A. Prowse, J. V. Ross, J. R. Saah, A. B. Shiels, , A. Lloyd

This paper proposes a gene drive method to localize population elimination to island populations by targeting locally fixed alleles, showing limited spread to non-target populations.

bioRxiv · Sep 7, 2019Evolutionary Biology

Evaluating Strategies For Reversing CRISPR-Cas9 Gene Drives

M. R. Vella, C. E. Gunning, A. L. Lloyd, F. Gould

The paper models gene drive reversal strategies using a discrete time population genetics model to evaluate their efficacy under different parameters and release scenarios.

bioRxiv · Aug 10, 2017Evolutionary Biology