Cell BiologybioRxivPreprint
Different NIPBL requirements of cohesin-STAG1 and cohesin-STAG2
D. Alonso-Gil, A. Cuadrado, D. Gimenez-Llorente…·A. Losada
The paper investigates the differential requirements of NIPBL for cohesin-STAG1 and cohesin-STAG2, showing NIPBL is not required for initial cohesin loading but is essential for loop extrusion and stabilization of cohesin-STAG2 at CTCF sites.