Histologic and Proteomic Remodeling of the Pulmonary Veins and Arteries in a Porcine Model of Chronic Pulmonary Venous Hypertension
A. U. Fayyaz, M. S. Sabbah, S. Dasari, L. G. Griffiths, H. M. DeBrock, M. C. Charlesworth, B. A. Borlaug, S. M. Jenkins, W. D. Edwards, M. M. Redfield
This paper identifies proteomic and signaling differences between pulmonary veins and arteries in a porcine model of chronic pulmonary venous hypertension, revealing unique endothelial barrier dysfunction and EndoMT in veins.
bioRxiv · Mar 26, 2021Physiology