Metal-independent ribonucleotide reduction powered by a DOPA radical in Mycoplasma pathogens
V. Srinivas, H. Lebrette, D. Lundin, Y. Kutin, M. Sahlin, M. Lerche, J. Eirich, R. Branca, N. Cox, B.-M. Sjöberg, M. Högbom
The paper identifies a metal-independent ribonucleotide reductase in Mycoplasma pathogens that uses a DOPA radical for DNA synthesis, differing from conventional RNRs.
bioRxiv · Jun 15, 2018Biochemistry