Author

M. Santer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1

Frequent Co-Authors

H. Uecker· 3 shared T. Dagan· 2 shared A. Garona· 1 shared A. Kupczok· 1 shared N. F. Huelter· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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3 shared papersEvolutionary Biology

H. Uecker

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3 papers

Recent·Most cited

Segregational drift hinders the evolution of antibiotic resistance on polyploid replicons

A. Garona, M. Santer, N. F. Huelter, H. Uecker, T. Dagan

This study shows that polyploid replicons hinder the evolution of antibiotic resistance due to segregational drift, affecting allele establishment probabilities.

bioRxiv · Feb 1, 2023Microbiology

Fixation dynamics of beneficial alleles in prokaryotic polyploid chromosomes and plasmids

M. Santer, A. Kupczok, T. Dagan, H. Uecker

This study develops a population genetics model for polyploid prokaryotes, showing that beneficial mutations can fix phenotypically before genotypically, creating a heterozygosity window.

bioRxiv · Jan 7, 2022Evolutionary Biology

Evolutionary rescue and drug resistance on multicopy plasmids

M. Santer, H. Uecker

The paper models how bacteria adapt to harsh environments using multicopy plasmids, finding that optimal copy numbers depend on environmental factors and plasmid dominance.

bioRxiv · Dec 23, 2019Evolutionary Biology