Dynamic membrane topology in an unassembled membrane protein
M. Seurig, M. Ek, G. Von Heijne, N. Fluman
This study shows that monomeric SMR proteins exhibit topological dynamics, with the N-terminal transmembrane helix switching between inserted and non-inserted states, and this dynamics is lost upon dimerization.
bioRxiv · Feb 13, 2019Biochemistry