Differentially polarized macrophages show diverse proangiogenic characteristics under normo- and hyperglycemic conditions
M. Shariatzadeh, C. Payan Gomez, W. A. Dik, P. J. Leenen
This study examines pro- and anti-angiogenic properties of human M1- and M2-like macrophages under normo- and hyperglycemic conditions, finding that IL-4 and IL-6 induce distinct phenotypes with mixed angiogenic gene expressions.
bioRxiv · Jan 12, 2024 · PreprintImmunology