Author

W. A. Dik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:non-human primate· 1 Research Focus:variant calling· 1

Frequent Co-Authors

C. Payan Gomez· 1 shared H. IJspeert· 1 shared M. S. Lourens· 1 shared M. Shariatzadeh· 1 shared N. Suratannon· 1 shared P. J. Leenen· 1 shared P. M. van Hagen· 1 shared P. van der Spek· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

C. Payan Gomez

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2 papers

Recent·Most cited

Differentially polarized macrophages show diverse proangiogenic characteristics under normo- and hyperglycemic conditions

M. Shariatzadeh, C. Payan Gomez, W. A. Dik, P. J. Leenen

This study examines pro- and anti-angiogenic properties of human M1- and M2-like macrophages under normo- and hyperglycemic conditions, finding that IL-4 and IL-6 induce distinct phenotypes with mixed angiogenic gene expressions.

bioRxiv · Jan 12, 2024 · PreprintImmunology

Did variants in inborn errors of immunity genes contribute to the extinction of Neanderthals?

Z. Zhou, S. M. A. Swagemakers, M. S. Lourens, N. Suratannon, P. van der Spek, V. A. S. H. Dalm, W. A. Dik, H. IJspeert, P. M. van Hagen

The paper investigates whether harmful immune-related genetic variants from Neanderthals contributed to their extinction by analyzing variants in inborn errors of immunity genes across Neanderthal and Denisovan genomes.

bioRxiv · Oct 19, 2022 · PreprintEvolutionary Biology