Alternative oxidase expression in mtDNA mutator mice improves blood phenotype but enhances inflammatory and stress responses in skeletal muscle
L. P. Pihlajamäki, S. Pirnes-Karhu, H. T. Jacobs, M. Szibor, A. Suomalainen-Wartiovaara
This study shows that expressing alternative oxidase in mtDNA mutator mice improves anemia but worsens skeletal muscle inflammation and stress responses.
bioRxiv · Mar 3, 2023 · PreprintMolecular Biology