Altering the bilayer motif in ERBB2 HER2 TMD and in ErbB HER TMD dimer causing in vitro and in vivo tumor suppression
The paper tests a compound targeting the TMD dimer motif of HER2 and HER1, showing tumor suppression and metastasis inhibition in vitro and in vivo.
bioRxiv · Mar 5, 2020Cancer Biology