Stability of Two-quartet G-quadruplexes and Their Dimers in Atomistic Simulations
B. Islam, P. Stadlbauer, M. Vorlickova, J.-L. Mergny, M. Otyepka, J. Sponer
This study uses molecular dynamics simulations to investigate the stability of two-quartet and four-quartet G-quadruplexes, finding that three quartets are needed for stable DNA GQs and RNA two-quartet GQs are weakly stable.
bioRxiv · Feb 25, 2020Biophysics