Biochemical analysis of the endoribonuclease activity of the human mitochondrial topoisomerase 1
C. P. J. Bader, E. Kasho, J. M. E. Forslund, M. Wessels, P. H. Wanrooij
This study investigates the endoribonuclease activity of hTop1mt and finds it less efficient than hTop1, explaining the tolerance of rNMPs in mtDNA.
bioRxiv · Mar 15, 2024 · PreprintBiochemistry