Madeline E. Smith

Amplification and attenuation of noisy expression by export processes

The paper analyzes how nuclear export processes modulate mRNA noise levels by deriving analytical expressions and showing that export rate and nuclear retention time distribution influence noise amplification or attenuation.

Stochastic delays suppress noise in a genetic circuit with negative feedback

This study analyzes a stochastic genetic circuit with negative feedback and time delays, showing that stochastic delays can reduce protein noise under certain conditions.

Autoregulation of pre-mRNA processing for buffering noisy gene expression

The paper analyzes how different feedback mechanisms affect protein noise levels in gene expression using a stochastic model and identifies optimal strategies under varying conditions.