EPHA4 Regulates the Transition between Mesenchymal and Hybrid States in TNBC
Wenchao Liu, H.W. Lee, Madeline H. Bungert, Long C. Nguyen, Aleksandra Kurowska, Thomas Jiyoung Lee, Geetha Priyanka Yerradoddi, Eva Amanda del Pilar Gallego Suárez, Marsha Rich Rosner
This study identifies EPHA4 as a regulator of the transition between mesenchymal and hybrid epithelial/mesenchymal states in TNBC, showing that its loss shifts cells toward hybrid states that enhance metastasis.
bioRxiv · Oct 6, 2026 · PreprintCancer Biology