THERM-D Uncovers Distinct Neural Mechanisms Separating Morning and Evening Body Temperature Rhythms in Drosophila
Tadahiro Goda, Olivia M Lopez, Richard Ramolete, Nils Reinhard, Nick Ulle, Ayumi Fukuda, Yujiro Umezaki, Kazim Rizvi, Madison G Aikawa, Roslyn Catiis, Victoria Z Marquez, Richard Ngo, Nikita Raj, Cora Fisher, Gregory T Bui, , Fumika N. Hamada
The paper introduces THERM-D, a machine learning tool to analyze body temperature rhythms in Drosophila, revealing that CRY-negative clock neurons regulate morning temperature rise independently of evening rhythms.
bioRxiv · Feb 20, 2026 · PreprintNeuroscience