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Maeve Bella Coleman

University of Virginia

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Systems Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

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Andrew Chaphiv· 1 shared Ben T. JordaniD· 1 shared Kristen M. NaegleiD· 1 shared Sam Crowl· 1 shared

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Andrew Chaphiv

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Systems BiologyCell SystemsPeer-reviewedJul 1, 2025

Systematic analysis of the effects of splicing on the diversity of post-translational modifications in protein isoforms using PTM-POSE

Sam Crowl, Maeve Bella Coleman, Andrew Chaphiv…·Kristen M. Naegle

This paper introduces PTM-POSE, a computational pipeline to analyze how alternative splicing affects post-translational modifications, and finds that 32% of PTMs are excluded from at least one Ensembl isoform.

10 citations

humanbulk RNA-seq

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