Unified high-resolution immune cell fraction estimation in blood tissue from birth to old age
Xiaolong Guo, Mahnoor Sulaiman, Alexander Neumann, Shijie Zheng, Charlotte A. M. Cecil, Andrew Erich Teschendorff, Bastiaan T. Heijmans
The paper develops a DNAm reference panel called UniLIFE to estimate immune cell fractions in blood tissue across the lifespan, identifying biomarkers for type-1 diabetes in infants and children.
Genome Medicine · May 27, 2025Peer-reviewedBioinformatics