Fast and accurate resolution of ecDNA sequence using Cycle-Extractor
Mahsa Faizrahnemoon, Jens Luebeck, King L. Hung, Suhas S.P. Rao, Gino Prasad, Ivy Tsz-Lo Wong, Hitesh Kandarpa, Matthew G. Jones, Paul S. Mischel, Howard Y. Chang, Kaiyuan Zhu, Vineet Bafna
Cycle-Extractor accurately reconstructs ecDNA structures from both short- and long-read sequencing data, outperforming existing methods in speed and completeness.
bioRxiv · Apr 15, 2026 · PreprintBioinformatics