Brain geometry matters in Alzheimer disease progression: a simulation study
Masoud Hoore, Jeffrey Kelling, Mahsa Sayadmanesh, Tanmay Mitra, Marta Schips, Michael Meyer‐Hermann
This study simulates Alzheimer's disease progression using a mathematical model of the Amyloid cascade hypothesis, showing that brain geometry and neural activity influence amyloid plaque formation and neural atrophy.
bioRxiv · Jul 24, 2020 · PreprintSystems Biology