Target Enrichment Enhances the Sensitivity of Sanger Sequencing for BRAF V600 Mutation Detection
Qiang Gan, Andrew Y. Fu, Fang Liu, Shuo Shen, Maidar Jamba, Wei Yong Liu, Mike Powell, Aiguo Zhang, Michael Y. Sha
This paper enhances Sanger sequencing sensitivity for detecting BRAF V600 mutations using target enrichment, achieving 0.04% variant allele frequency detection.
bioRxiv · Aug 14, 2021 · PreprintMolecular Biology