LRP2 controls sonic hedgehog-dependent differentiation of cardiac progenitor cells during outflow tract formation
Annabel Christ, Maike Marczenke, Thomas E. Willnow
This study identifies LRP2's role in maintaining sonic hedgehog-dependent cardiac progenitor cells during outflow tract formation, leading to conotruncal malformations when disrupted.
Human Molecular Genetics · Sep 7, 2020Peer-reviewedDevelopmental Biology